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MultiNode Organoid Chip

Platform Overview

The MultiNode Organoid Chip is a microfluidic platform that connects multiple organoid culture nodes within a single chip, enabling inter-organ communication, high-throughput testing, and controlled microenvironment manipulation. Each kit includes the microfluidic chip, culture plate adapters, tubing system, and perfusion interface. Users can customize node arrangement, flow rates between nodes, and plate format, while the base chip geometry and material remain fixed.

Key Features & Advantages

  • Multi-node connectivity – allows organoid nodes to communicate, simulating tissue-tissue interactions.

  • Controlled microfluidic environment – precise perfusion and flow control for each node.

  • High-throughput capability – multiple chips can be operated simultaneously for large-scale experiments.

  • Integration with standard workflows – compatible with imaging, sampling, and common organoid culture procedures.

  • Facilitates complex studies – supports drug screening, mechanobiology, and inter-organ signaling research.

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Collaboration / Customization Options

We welcome collaborators interested in testing the platform or developing custom microfluidic protocols. Adjustable parameters include:

  • Node arrangement: customizable layout for inter-organ connections

Custom collaborations can involve co-developing chip designs, optimizing inter-node flow conditions for specific organoid models, or pursuing joint publications.

Advancing 3D biological research through innovative microenvironment engineering and collaborative scientific development.

School of Mechanical & Aerospace Engineering (MAE),

Nanyang Technological University (NTU),

Singapore 639798

 

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